I had to turn down a contract because it was a vanity press masquerading as a traditional publisher.
I wrote a vampire novel. There's nothing like a vampire novel to let your creativity flow, unencumbered and free. Unlike any other kind of fiction, the vampire novel immediately brings up all of the fundamental moral problems that face mortal humans.
So I'm taking the plunge: e-publishing. No print-on-demand self-publisher for me. No boxes of books. No trucks and no book chains. I'm going all electronic, baby!